Endocrine system

Homeostasis

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“The internal environment is to the cell as the external environment is to the human organism as a whole- the source of the factors and influences which support life.”

” On the other hand, the environment is also the source of influences that disturb cellular function and derange the balance that supports the total body economy.

The maintenance of optimum internal balance is homeostasis.

Departures from homeostatic limits are produced by alteration in the fluid matrix which in turn is secondary to altered circulatory dynamics.

Therefore one must look to variations in the integrating and communicating systems as being the cause of such aberration, and must seek means of utilizing the integrating systems to correct these aberrations, thereby returning cellular function to homeostatic limits ans health. ”

“Osteopathic Medecine”

From HOAG, COLE, BRADFORD

Edition MC GRAW-HILL

1969

Disorders of the Endocrine System,

William Baldwin, Jr

Chapt 16 p. 228

Dysfunction, disease

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“If we accept the concept that each of us consists of an orderly grouping of cells living within a fluid matrix, and that health represents a situation in which the internal environment is maintained within homeostatic limits by the integrating systems of the body, then it is logical to postulate that disease is an alteration in these mechanisms which permits or forces a departure from these homeostatic limits, resulting in altered function or physiology.”

“Osteopathic Medecine”

From HOAG, COLE, BRADFORD

Edition MC GRAW-HILL

1969

Disorders of the Endocrine System,

William Baldwin, Jr

Chapt 16

p. 228

Nervous & Endocrine System

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” Within the internal environment, endocrine regulation is preeminent.

Cellular function is regulated and governed by hormones produced in the endocrine glands and conveyed to the appropriate site by the circulatory system.

The hormones are catalysts only – they do not add to the cells or alter their genetically determined purpose but are necessary to instigate and control specific cellular mechanisms which are implemented by enzymes.

Although the hormones and enzymes are among the latest physiologic catalysts to be discovered, they probably were one of the first means of regulation to evolve- a primitive system of controls which later surrendered part of its independence to the nervous system in the interests of faster and more specific action, particularly in emergencies.

Thus the endocrine system, as one of the major physiologic regulators, is now recognized as partly autonomous and partly associated with the neurologic coordinating system.

This is how hormone function can be influenced by psychological and emotional forces and can in turn initiate profound changes in both psychologic and physiologic aspects of nervous function.As one studies the increasing evidence of neuroendocrine interrelationships, it appears more and more certain that the nervous and endocrine systems are the prime regulators.

Viewed in this light, neuroendocrine mechanisms can be seen to operate as both cause and effect of physiologic events.”

“Osteopathic Medecine”

From HOAG, COLE, BRADFORD

Edition MC GRAW-HILL

1969